Applications Library - Separation Science Mass Spectrometry

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Discovering the Scent of Celery: HS-SPME, GC-TOFMS,and Retention Indices for the Characterization of Volatiles

Here, we analyze a celery sample with HS-SPME coupled to GC-TOFMS. Hundreds of analytes were detected in this complex sample with many contributing important odor characteristics. The resulting data provides valuable information to characterize the aroma profile of celery by determining individual analytes.Learn more...

Comparison of Aroma and Flavor Profiles of Strawberry-Flavored Candy and Fresh Strawberries

A fresh strawberry and a strawberry-flavored candy were analyzed and compared on LECO Pegasus® BT GC-TOFMS. Hundreds of analytes were determined and deconvolution provided the ability to fight chromatographic coelutions uncovering differences that were hidden in the TIC and provided more insight to the flavor characteristics. Compound classes were investigated with lactones, ethyl esters, and sesquiterpenes compared between each sample.Learn more...

Discovery of Environmental Pollutants at an Electronic Waste Recycling Facility by Pegasus® GC-HRT 4D

This study aimed to discover new and emerging organic contaminants in the environment of an e-waste recycling facility using comprehensive two-dimensional gas chromatography high resolution time-of-flight mass spectrometry. GC×GC-HRT is a powerful tool for the comprehensive analysis and chemical characterization of analytes in complex matrices.Learn more...

Pegasus® BT ! Discovery of Sulfur-Containing Compounds in Broccoli with GC-TOFMS

The Pegasus® BT rapidly provided information on these analytes in order to determine those that were sample-distinguishing. ChromaTOF brand software's automated data analysis tools and peak property filters were used to specifically focus on sulfur-containing compounds. GC-TOFMS let you uncover more than in your standard analysis. Ref. 203-821-531Learn more...

Pegasus® BT ! Tasting “Weird and Wild” Jelly Bean Flavors Using HS SPME Gas Chromatography Mass Spectrometry

This note demonstrates the ease-of-use and capabilities of a LECO's Pegasus BT - GC-TOFMS a benchtop time-of-flight mass spectrometer to effectively differentiate exotic flavor profiles in store-purchased jelly beans. Ref. 203-821-529Learn more...

Pegasus® BT ! EPA Method 8270 Semivolatile Organic Compounds Analysis on the Benchtop GC-TOFMS

This application note details the performance of the Pegasus BT for EPA Method 8270, and demonstrates how to meet and exceed the method requirements. The sensitivity surpasses what most laboratories are currently achieving for this method, expanding the typical linear dynamic range and sample throughput. The StayClean ion source will further increase uptime as it is extremely low maintenance. Ref. 203-821-530Learn more...

Pegasus® BT ! Rapid Screening Analysis for Barbiturates in Human Urine by GC-TOFMS

Data showed that the LECO Pegasus BT instrument is capable of detecting well below the minimum cutoff level required by the mandatory guidelines. Excellent calibration linearity was demonstrated for barbiturates in the urine extracts. Each analysis completed in less than nine minutes Ref. 203-821-528Learn more...

Pegasus® BT ! Metabolomic Profiling of Corn and Rice Extracts Using a Benchtop GC-TOFMS

Comprehensive metabolomics data was acquired in just over 10 minutes. Metabolites were confidently identified via automated, comprehensive data processing by ChromaTOF software which involved peak find, spectral similarity searches against large well-established databases, and by leveraging retention index values. Ref. 203-821-526Learn more...

New Pegasus® BT ! Analysis of Fats in Food Products with GC-TOFMS

While FID is a standard detector for these analyses, we present some scenarios where MS detection, in particular TOFMS with deconvolution capabilities, offers key benefits to see what you are missing in your fats analysis. The Pegasus BT is well-suited for routine screening applications, such as this analysis for fats in foods. Ref. 203-821-525Learn more...

New Pegasus® BT ! Fast Pesticide Residue Analysis in Food with a Benchtop GC-TOFMS

The combination of excellent linearity over greater than 4 orders of magnitude of dynamic range and sub ppb detection limits in matrix (LOD was ≤ 0.1 ppb for 74% of the pesticides ) demonstrate that the Pegasus BT is a powerful tool for quantitative pesticide residue analysis Ref. 203-821-524Learn more...

New Pegasus® BT ! Characterization of Fruit Tea Beverages

The Pegasus BT provides a complete aroma profile for every sample, from every run. The ability to determine individual analytes offered the opportunity to compare and contrast the samples and learn more from a standard analysis. Ref. 203-821-523Learn more...

New Pegasus® BT! Battling Fuel-Washing: Detection of Accutrace S10 in Commercial Diesel Samples

LECO Pegasus BT GC-TOFMS easily met the requirement. Without the need for any additional separation methods or sample preparation spiked diesel samples were analyzed in less than 15 minutes, allowing for quantitation in the concentration range of 2500 ppb to 10 ppb Ref. 203-821-522Learn more...

New Pegasus® BT! Rapid Screening for Contact Allergens in Perfumes with GC-TOFMS

A rapid GC-TOFMS method was developed to separate and detect a target set of 24 regulated contact allergens in approximately 5 minutes. In addition to the target allergens, the data also provides excellent characterization information for non-targeted aroma analytes within complex perfume samples. Ref. 203-821-519Learn more...

New Pegasus® BT! ASTM D5769: A Solution for Determination of High-Concentration Aromatic Compounds in Finished Gasoline

LECO's Pegasus BT GC-TOFMS a benchtop time-of-flight mass spectrometer easily satisfies the method requirements for sensitivity, ion ratios, and calibration linearity, providing a robust solution for analysis of the aromatic compounds, without saturation of the ion source. Ref. 203-821-518Learn more...

New Pegasus® BT! Quantification of 2,4,6-trichloroanisole to Detect Cork Taint Fault in Wine

The Pegasus BT provides full m/z range data and sensitivity which make it ideal for screening target analytes and/or general unknowns. The better than nominal mass information generated by the Pegasus BT allowed for further distinction of the target analyte from a matrix interference at the very lowest concentrations. Ref. 203-821-517Learn more...

Quantification of Contact Allergens in Personal Care Products with GC and Full Mass Range TOFMS

Pegasus HT and the ChromaTOF deconvolution and calibration features demonstrated the potential of this technology for the investigation of contact allergens in cosmetic and personal care products. In particular, the HT's full mass range sensitivity and speed with unparalleled deconvolution capabilities allowed to see peaks that may be hidden in a standard analysis. Ref. 203-821-515Learn more...

Detection of Cork Taint Fault in Wine Using HS-SPME and GC-TOFMS for the Quantification of 2,4,6-trichloroanisole

The coupling of a HS-SPME sample preparation step together with the power of the Pegasus HT and the ChromaTOF deconvolution and calibration features, allowed the detection of very low concentration- at parts-per-trillion levels- of 2,4,6-trichloroanisole (TCA) in a real wine samples. This component, as well established, is responsible for the cork taint fault also at very low concentrations. Ref. 203-821-516Learn more...

Differentiation of Fresh and Oxidized Wine Samples with HS-SPME, GC-TOFMS, and GC×GC-TOFMS

Pegasus HT and Pegasus 4D systems were used to differentiate two wine samples namely one fresh and one oxidized by the presence of oxygen inside the bottle. Thanks to the increased peak capacity and sensitivity offered by the coupling of a secondary column on the GCXGC system, it was possible to assign correctly the components formed during the oxidation process. Furthermore, LECO’s Deconvolution tool allowed the correct identification of the components well resolved or masked from the sample matrix. Ref. 203-821-514Learn more...

Quantitative Analysis of GHB in Hair in forensics

The potential of the GC-HRT system together with the unique ChromaTOF-HRT's High Resolution Deconvolution (HRD ) and Target Analyte Finding (TAF) has been revealed to be valid tool for the determination and quantification of the GHB in hair samples and, also to make a screening of other non-target chemicals coming from the same sample such as acids, amino acids, diacids, fatty acids, esters, amides and monoacylglycerides.Learn more...

How Comprehensive is Your Analysis? Human Molecular Profiling by HR TOF-MS

The LECO Pegasus GC-HRT instrument was used to monitor behaviour (e.g., drug abuse) and also to perform more comprehensive molecular profiling following a suitable urine sample preparation step. Ref: 203-821-503Learn more...
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