ChromaTOF Software for Separation Science Line

TOF_SOFT
ChromaTOF-upd

Automated Peak Find

LECO’s patented Automated Peak Find and True Signal Deconvolution algorithms serve as a foundation for identifying a sample's true chemical content.

Automation

Synchronized with Automated Peak Find, mass spectra for each analyte is automatically extracted free of interferences from the system background, matrix background, and coeluting analytes.

Description

Designed with your laboratory in mind and with outstanding ease-of-use, ChromaTOF encapsulates the industry’s most advanced qualitative and quantitative capabilities into one easy-to-use, seamless data-handling system.

Benefits of LECO ChromaTOF:

  • Easy access to common functions with user-friendly interfaces
  • Secure data file access and audit ability with definable access rights with the User Permissions feature
  • Maximise chromatographic resolution with the ability to modify modulation settings within each GCxGC chromatographic run for a more specialized analysis.
  • Decrease the need for dilution and re-analysis of high concentration samples saves you analysis time using ChromaTOF’s Extended Range Calibration algorithm
  • Ensure accurate isotopic spectral patterns, extend the dynamic range, and enhance system robustness with ChromaTOF’s Automatic Mass Defect adjustment
  • Reduce routine tasks and free up operator time with Automatic tuning within user-defined Quality Control methods
  • Report non-calibrated compounds in a Semi-Quantitative Analysis approach with ease

Operation

Versatile with a logical and structured work flow, ChromaTOF guides you through each task to create fully automated data acquisition and data processing protocols to final data summary reports.  See exactly what you want and when you want with ChromaTOF’s customisable workspaces for every individual and every task.

Features and Benefits:

  • Display important peak labels and peak markers on contour and surface plots using enhanced graphics for GCxGC users.
  • Easily export and further analyze Statistical Compare results and Fisher Ratios with simple export options
  • Importable ready-to-use workspace templates for access to preferred user interfaces and reduced set-up times
  • True Signal Deconvolution®, Automated Peak Find, and Extended Range Calibration algorithms
  • Semi-Quantitative Analysis for the reporting of non-calibrated compounds
  • Compare feature allows for fast and easy sample comparison and the ability to quickly determine quality lots
  • Reduce the frustrations of shared workstations with customised and personalised user interface layouts
  • Automatically export data to PDF, CSV, ANDI MS, NETCDF, or Raw file formats
  • Automatically identify potential analyte matches without the need for importing or exporting data using the LECO-Fiehn Metabolomics Library featuring over 1,100 spectra of 700 unique metabolomics for metabolite identification in your most complex samples. Fully integrated within ChromaTOF, the library works seamlessly with the software's Library Search function.

Application

LECO’s versatile instrumentation can be used to perform a wide range of applications. Please find below a selection of application notes for the most popular applications. Contact our sales and application specialists for more details.

Resample, Petroleum

The Use of Resample to Improve Data Processing for GCxGC-TOFMSLearn more...

Forensics, Cause of Death

The Compare Feature of ChromaTOF —Its Use in Forensic Chemistry to Assist with the Determination of the Cause of DeathLearn more...

Peak Marker, Plots

"Peak Marker Only" Plots for GCxGC-TOFMSLearn more...

Options & models

Options

Various options are available for this product. Contact our sales and application specialists to select the right configuration for your application.

Reference Compare Quickly compare on a peak-by-peak and mass spectrum-by-mass spectrum basis whole chromatograms of various samples.  Offering an ideal tool for comparing batches of good and bad quality food or cosmetic products after analysis by Gas Chromatography Time-of-Flight Mass Spectrometry (GC-TOFMS).  The LECO ChromaTOF software package contains a unique Sample Comparison algorithm that provides quick answers to complex questions.

Statistical Compare Unlimited data files can be automatically and statistically compared and reported in LECO’s Statistical Compare software tool.  Simplify metabolomic datasets by aligning the same analyte peaks over multiple samples by determining a common quantification mass effortlessly. Identify significant differences in analyte concentrations using the Statistical Compare Fisher ratio feature that finds common analytes across multiple samples.  The features of Statistical Compare can be applied to both GC-TOFMS and GCxGC-TOFMS data.

Classifications Classifications is a feature of the data processing package for GCxGC of LECO's proprietary ChromaTOF software.  Classifications utilize the structured nature of a GCxGC chromatogram to organize related analytes into user defined groups. Classifications may also be used to selectively process, or exclude, regions of the chromatogram and can be combined with ChromaTOF’s Scripting tools.

Models

Each instrument can be configured to meet your individual lab needs. Contact our sales and application specialists to select the right configuration for your application.
Scripting Tools Scripting is an ideal tool for Petroleomics, Biofuel, Food and Flavour, Metabolomics and Environmental applications to unravelling complexity in heavy matrix sample sets.  Versatile and incredibly simple to create, Scripting can return relative intensity of the specified mass abundance, the mass of rank index from the list of masses sorted by intensity and much, much more.  Spectral searching offers the ability to identify compounds in a chromatogram using mass spectral characteristics across the entire chromatographic plane (cached scripts) and within specific classification regions (scripts used with classification).  On top of all this, Scripting gives fully automated data output when included in the data processing method work flows or can be computed during data review.  Increase selectivity and automatically unravel complex samples with operator defined rules that return valuable information associated with a point in the GCxGC chromatographic plane based on mass spectral data.

Documentation

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