Metabolomics, Biomarkers, Plasma, Lean, Fat, Obese Rats

DOCUMENT: Application | Ref: 203-821-405Download
Category: Metabolomics, Separation Science Mass Spectrometry, TOF Mass Spectrometry

Utilization of GCxGC-TOFMS to Screen for Potential Metabolite Differences in Pooled Plasma Samples from Lean, Fat, and Obese Rats

The analysis of derivatized complex blood plasma demonstrates the enhanced detection and increased peak capacity available with GCxGC-TOFMS using the LECO Pegasus 4D instrument. The GCxGC-TOFMS results for the lean, fat, and obese sample pools demonstrates how GCxGC separates and resolves components that would otherwise totally coelute and be buried under high concentration analytes in one-dimensional chromatography.