Anabolic Steroids, Doping Control

DOCUMENT: Application | Ref: 203-821-395Download
Category: Forensics Toxicology, Separation Science Mass Spectrometry, TOF Mass Spectrometry

Analysis of Anabolic Steroids for Doping Control Purposes by GC-TOFMS and GCxGC-TOFMS

One-dimensional GC-TOFMS provides satisfactory results for the purpose of screening anabolic steroids in urine. The signal-to-noise ratios of minimum 3 ion traces were sufficiently high at 2 ng/mL concentration level (except epimethendiol). However, the spectral match factors were lower than 800 for some compounds, and the correct identification of ultra-trace levels of steroids was difficult in some cases due to the high complexity of urine matrix.